Opioid overdoses in large cities increase by 54 percent in 16 states.The Midwestern region saw opioid overdoses increase 70 percent from July 2016 through September 2017.Opioid overdoses increased 30 percent from July 2016 through September 2017 in 52 areas in 45 states.About 80 percent of people who use heroin first misused prescription opioids.An estimated 4 to 6 percent who misuse prescription opioids transition to heroin.Between 8 and 12 percent develop an opioid use disorder.Roughly 21 to 29 percent of patients prescribed opioids for chronic pain misuse them.The Centers for Disease Control and Prevention estimates that the total "economic burden" of prescription opioid misuse alone in the United States is $78.5 billion a year, including the costs of healthcare, lost productivity, addiction treatment, and criminal justice involvement. The misuse of and addiction to opioids, including prescription pain relievers, heroin, and synthetic opioids such as fentanyl, is a serious national crisis that affects public health as well as social and economic welfare.
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